/malignant Leydig cell tumor

malignant Leydig cell tumor

MONDO:0000377

Also Known As

Leydig cell cancerLeydig cell tumor, malignantcancer of Leydig cellmalignant Leydig cell neoplasmmalignant interstitial cell neoplasmmalignant neoplasm of Leydig cellmalignant interstitial cell tumormalignant interstitial cell tumour

Definition

A Leydig cell tumor characterized by large tumor size, the presence of cytologic atypia, increased mitotic activity, necrosis, and vascular invasion. Approximately 10% of the testicular Leydig cell tumors show malignant characteristics and metastasize. Leydig cell tumors of the ovary follow a benign clinical course.