/cerebral arteriopathy with subcortical infarcts and leukoencephalopathy

/cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1

cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1

Rare Disease

MONDO:0000914

Also Known As

cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathyCADASILCADASIL 1CADASIL syndromeCADASIL type 1CADASIL1CASILautosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 1cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1dementia, hereditary multi-infarct typehereditary multi-infarct dementiacerebral arteriopathy with subcortical infarcts and leukoencephalopathyfamilial vascular leukoencephalopathy

Definition

A CADASIL characterized by migraine, strokes, and white matter lesions that has material basis in heterozygous mutation in the NOTCH3 gene on chromosome 19p13.