/intrahepatic cholangiocarcinoma

intrahepatic cholangiocarcinoma

Rare Disease

MONDO:0003210

Also Known As

ICCcholangiocarcinoma, intrahepatic, malignantintrahepatic Cholangiocellular carcinomaintrahepatic bile duct cancer (cholangiocarcinoma)intrahepatic bile duct carcinomaintrahepatic carcinoma of bile ductintrahepatic carcinoma of the bile ductintrahepatic cholangiocarcinomaintrahepatic cholangiocarcinoma (bile duct cancer)peripheral cholangiocarcinomaIHCH

Definition

A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.