/testicular yolk sac tumor

testicular yolk sac tumor

Rare Disease

MONDO:0003402

Also Known As

testicular yolk Sac neoplasmtesticular yolk sac tumortestis yolk sac tumortestis yolk sac tumourOrchidoblastomaendodermal sinus neoplasm of testisendodermal sinus neoplasm of the testisendodermal sinus tumor of testisendodermal sinus tumor of the testisendodermal sinus tumour of testisendodermal sinus tumour of the testisendodermal-sinus tumorendodermal-sinus tumourtesticular endodermal sinus neoplasmtesticular endodermal sinus tumortesticular endodermal sinus tumouryolk Sac neoplasm of testisyolk Sac neoplasm of the testisyolk Sac tumor of testisyolk Sac tumor of the testisyolk Sac tumour of testisyolk Sac tumour of the testisyolk sac tumoryolk sac tumour

Definition

A non-seminomatous malignant germ cell tumor arising from the testis. It affects infants, young children, and postpubertal males. It is the most frequently seen testicular neoplasm during childhood. The vast majority of patients present with an asymptomatic scrotal mass. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). It metastasizes to distant anatomic sites. Prognostic factors relate to the clinical stage and the degree of AFP elevation.