/hereditary breast ovarian cancer syndrome

hereditary breast ovarian cancer syndrome

Rare Disease

MONDO:0003582

Also Known As

BRCA1- and BRCA2-associated hereditary breast and ovarian cancerBRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC)Hereditary Breast and Ovarian Cancer Syndromefamilial breast and ovarian cancer syndromefamilial breast/ovarian cancer (BRCA1, BRCA2)hereditary breast and ovarian cancerhereditary breast and ovarian cancer syndromehereditary breast ovarian cancer syndromehereditary breast/ovarian cancer (BRCA1, BRCA2)HBOC syndromeHBOC syndromeshereditary breast ovarian cancersyndrome, HBOCsyndromes, HBOC

Definition

An autosomal dominant inherited syndrome caused by mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer.