A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include eosinophilia, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn wd, Semin Arthritis Rheum 1997 Jun;26(6):788-93)
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pulmonary eosinophilia
MONDO:0004802
disseminated eosinophilic collagen disease
MONDO:0004803
idiopathic hypereosinophilic syndrome
MONDO:0011895
primary hypereosinophilic syndrome
MONDO:0017833
secondary hypereosinophilic syndrome
MONDO:0017834
hypereosinophilia of undetermined significance
MONDO:0100059