/pancreatic endocrine carcinoma

pancreatic endocrine carcinoma

Rare Disease

MONDO:0005893

Also Known As

Pancreatic Neuroendocrine cancercarcinoma of endocrine pancreascarcinoma, islet cell, malignantendocrine pancreas carcinomahigh grade pancreatic neuroendocrine carcinomahigh-grade pancreatic neuroendocrine carcinomaislet cell cancerislet cell carcinomaislet cell carcinoma (morphologic abnormality)malignant islet cell tumormalignant islet cell tumourmalignant neoplasm of islets of Langerhansmalignant pancreatic endocrine tumormalignant pancreatic endocrine tumourpancreatic NECpancreatic NEC G3pancreatic endocrine cancerpancreatic endocrine carcinomapancreatic neuroendocrine carcinomapoorly differentiated pancreatic endocrine carcinomapoorly-differentiated NEN of pancreaspoorly-differentiated neuroendocrine neoplasm of pancreaspoorly-differentiated pancreatic NENpoorly-differentiated pancreatic neuroendocrine neoplasmneuroendocrine carcinoma of pancreas

Definition

An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 HPF. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma.