/gastric mucosa-associated lymphoid tissue lymphoma

gastric mucosa-associated lymphoid tissue lymphoma

Rare Disease

MONDO:0006226

Also Known As

MALT lymphoma of stomachMALT lymphoma of the stomachMALToma of stomachMALToma of the stomachgastric MALT lymphomagastric MALTomagastric mucosa-associated lymphoid tissue lymphomaprimary MALT lymphoma of stomachprimary MALT lymphoma of the stomachprimary gastric B-cell MALT lymphomaprimary gastric MALT lymphomastomach MALT lymphoma

Definition

A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.