/adrenal cortex carcinoma

adrenal cortex carcinoma

Rare Disease

MONDO:0006639

Also Known As

adrenal cortex canceradrenal cortical tumorsadrenal cortical tumoursadrenocortical cancercancer of the adrenal cortexmalignant adrenocortical tumormalignant adrenocortical tumourmalignant neoplasm of adrenal cortexmalignant tumor of adrenal cortexmalignant tumour of adrenal cortexACCAdenoid Cystic Carcinomaadenocarcinoma, adrenocortical, malignantadrenal cortex adenocarcinomaadrenal cortex carcinomaadrenal cortical adenocarcinomaadrenal cortical carcinomaadrenal cortical carcinoma (morphologic abnormality)adrenocortical carcinomaadrenocortical carcinoma (disease)carcinoma of adrenal cortexcarcinoma of the adrenal cortexcarcinoma, adrenocortical, malignantcortical cell carcinoma

Definition

A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival.