Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides serum sickness and the arthus reaction, evidence supports a pathogenic role for immune complexes in many other immune system diseases including glomerulonephritis, systemic lupus erythematosus (lupus erythematosus, systemic) and polyarteritis nodosa.
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autoimmune disease, multisystem, infantile-onset
MONDO:0000213
autoimmune disorder of endocrine system
MONDO:0000569
autoimmune disorder of exocrine system
MONDO:0000586
autoimmune disease of ear, nose and throat
MONDO:0000587
autoimmune disorder of gastrointestinal tract
MONDO:0000588
autoimmune disorder of musculoskeletal system
MONDO:0000589