/pseudohypoparathyroidism type 1A

pseudohypoparathyroidism type 1A

Rare Disease

MONDO:0007078

Also Known As

AHO-PHP syndrome IaAlbright hereditary osteodystrophyAlbright hereditary osteodystrophy with multiple hormone resistanceAlbright hereditary osteodystrophy-PHP syndrome IaAlbright's hereditary osteodystrophyPHP1APseudohypoparathyroidism IaPseudohypoparathyroidism type 1AAHOPHP 1APseudohypoparathyroidism, type 1APseudohypoparathyroidism, type IA

Definition

A type of pseudohypoparathyroidism (PHP) characterized by renal resistance to parathyroid hormone (PTH), resulting in hypocalcemia, hyperphosphatemia, and elevated PTH; resistance to other hormones including thydroid stimulating hormone (TSH), gonadotropins and growth-hormone-releasing hormone (GHRH); and a constellation of clinical features known as Albright hereditary osteodystrophy (AHO).