/multicentric carpo-tarsal osteolysis with or without nephropathy

multicentric carpo-tarsal osteolysis with or without nephropathy

Rare Disease

MONDO:0008152

Also Known As

idiopathic multicentric osteolysis with or without nephropathymulticentric carpo-tarsal osteolysis with or without nephropathyCarnevale canun Mendoza syndromeMCTOmulticentric carpotarsal osteolysis syndromemulticentric osteolysis nephropathymulticentric osteolysis, autosomal dominantosteolysis, hereditary, of carpal bones with or without nephropathy

Definition

Idiopathic multicentric osteolysis is a very rare syndrome characterized by progressive loss of bone, usually the capsal and tarsal bones, resulting in deformity and disability, as well as chronic renal failure in many cases. The bone and renal disorders are sometimes associated with intellectual deficit and facial abnormalities.