/aplasia of lacrimal and salivary glands

aplasia of lacrimal and salivary glands

Rare Disease

MONDO:0008397

Also Known As

ALSGaplasia of lacrimal and salivary glandscongenital absence of lacrimal puncta and salivary glandsparotid aplasia or hypoplasiasalivary glands, absence ofsalivary glands, absence of, include

Definition

Aplasia of the lacrimal and salivary glands (ALSG) is a rare autosomal dominant disorder characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary glands leading to varying features since infancy such as recurrent eye infections, irritable eyes, epiphora, xerostomia, dental caries, dental erosion and oral inflammation.