/Behr syndrome

Behr syndrome

Rare Disease

MONDO:0008858

Also Known As

Behr syndromeBEHRSoptic atrophy in early childhood, associated with ataxia, spasticity, intellectual disability, and posterior column sensory lossoptic atrophy in early childhood, associated with ataxia, spasticity, mental retardation, and posterior column sensory lossoptic atrophy, infantile hereditary, Behr complicated form ofoptic atrophy, infantile hereditary, with neurologic abnormalities

Definition

A disorder characterized by early-onset optic atrophy along with neurological features, including ataxia, spasticity, and intellectual disability. Other signs and symptoms may be present and vary from person to person. This condition is caused by mutations in the OPA1 gene. It is inherited in an autosomal recessive manner. Treatment depends on the specific signs and symptoms seen in the patient.