/lissencephaly type 1 due to doublecortin gene mutation

lissencephaly type 1 due to doublecortin gene mutation

Rare Disease

MONDO:0010239

Also Known As

X-linked lissencephaly type 1lissencephaly type 1 due to doublecortin gene mutationlissencephaly, X-linkedlissencephaly, X-linked, type 1subcortical laminal heterotopia, X-linkedDc syndromeDouble cortex syndromeLISXLISX1X-linked lissencephalyXLISXlislissencephaly X-linkedlissencephaly and agenesis of corpus callosumlissencephaly, X-linked, 1subcortical band heterotopia, X-linkedsubcortical laminar heterotopia, X-linkedsubcortical laminar heterotopia, X-linked,

Definition

Type 1 lissencephaly due to doublecortin (DCX) gene mutations is a semi-dominant X-linked disease characterized by intellectual deficiency and seizures that are more severe in male patients.