/syndactyly type 8

syndactyly type 8

Rare Disease

MONDO:0010669

Also Known As

FGF16 non-syndromic syndactylyfusion of metacarpals 4 and 5metacarpal 4-5 fusion, X-linked recessivenon-syndromic syndactyly caused by mutation in FGF16MF4metacarpal 4-5 fusionmetacarpals 4 and 5 fusion

Definition

Syndactyly type 8 is a rare, genetic, non-syndromic, congenital limb malformation characterized by unilateral or bilateral fusion of the fourth and fifth metacarpals with no other associated abnomalities. Patients present shortened fourth and fifth metacarpals with excessive separation between their distal ends, resulting in marked ulnar deviation of the little finger and an inability to bring the fifth finger in parallel with the other fingers.