/MELAS syndrome

MELAS syndrome

Rare Disease

MONDO:0010789

Also Known As

MELAS syndromemitochondrial encephalomyopathy, lactic acidosis and strokemitochondrial encephalomyopathy, lactic acidosis and stroke-like episodesmitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodesmitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodesMELASmitochondrial encephalomyopathy lactic acidosis and stroke-like episodes

Definition

MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive multisystemic disorder characterized by encephalomyopathy, lactic acidosis, and stroke-like episodes. Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations.