/autosomal recessive juvenile Parkinson disease 2

autosomal recessive juvenile Parkinson disease 2

Rare Disease

MONDO:0010820

Also Known As

PRKN young-onset Parkinson diseaseParkinson disease, juvenile, type 2autosomal recessive juvenile Parkinson disease 2autosomal recessive juvenile Parkinson disease type 2young-onset Parkinson disease caused by mutation in PRKNJPPARK2PDJParkinson disease 2Parkinson disease 2, autosomal recessive juvenileParkinson disease autosomal recessive, early onsetParkinson disease, juvenile, autosomal recessiveParkinsonism, early onset, with diurnal fluctuationParkinsonism, early-onset, with diurnal fluctuationautosomal recessive juvenile Parkinson diseaseautosomal recessive juvenile Parkinson's disease 2juvenile parkinsonism

Definition

A group of disorders which feature impaired motor control characterized by bradykinesia, muscle rigidity; tremor; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see Parkinson disease), secondary parkinsonism (see Parkinson disease, secondary) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the basal ganglia.