/familial sick sinus syndrome

familial sick sinus syndrome

Rare Disease

MONDO:0012061

Also Known As

familial sinus node dysfunctionhereditary sick sinus syndromeSSS1sick sinus syndrome 1, autosomal recessive

Definition

Sick sinus syndrome is a rare cardiac rhythm disease, usually of the elderly, characterized by electrocardiographic findings of sinus bradycardia, atrial fibrillation, atrial tachycardia sinus arrest, or sino-atrial block, and that manifest with symptoms like syncope, dizziness, palpitations, fatigue, or even heart failure. It results from malfunction of the cardiac conduction system, probably secondary to degenerative fibrosis of nodal tissue in the elderly or secondary to cardiac disorders in younger patients.