/insulin-resistance syndrome type A

insulin-resistance syndrome type A

Rare Disease

MONDO:0012520

Also Known As

insulin resistant diabetes mellitus with acanthosis nigricans and hyperandrogenismtype A insulin resistance syndromeIran, type adiabetes mellitus, insulin-resistant, with acanthosis nigricansdiabetes mellitus, insulin-resistant, with acanthosis nigricans, type ainsulin receptor, defect in, with insulin-resistant diabetes mellitus and acanthosis nigricansinsulin-resistant acanthosis nigricans, type A

Definition

Type A insulin-resistance syndrome belongs to the group of extreme insulin-resistance syndromes (which includes leprechaunism, the lipodystrophies, Rabson-Mendenhall syndrome and type B insulin resistance syndrome) and is characterized by the triad of hyperinsulinemia, acanthosis nigricans (skin lesions associated with insulin resistance), and signs of hyperandrogenism in females without lipodystrophy and who are not overweight.