/recurrent infections associated with rare immunoglobulin isotypes deficiency

recurrent infections associated with rare immunoglobulin isotypes deficiency

Rare Disease

MONDO:0013576

Also Known As

IgG subclass deficiency with IgA subclass deficiencyisolated IgG subclass deficiencykappa light chain deficiencykappa-chain deficiencyrecurrent infections associated with rare immunoglobulin isotypes deficiencyIGKCDIMMUNOGLOBULIN kappa LIGHT chain deficiencykappa chain deficiencyselective IgG subclass deficiency

Definition

Deficiencies in immunoglobulin (Ig) isotypes (including: isolated IgG subclass deficiency, IgG subclass deficiency with IgA deficiency and kappa chain deficiency) are primary immunodeficiencies that are often asymptomatic but can be characterized by recurrent, often pyogenic, sinopulmonary infections.