autoimmune lymphoproliferative syndrome type 4

Rare Disease

MONDO:0013767

Also Known As

ALPS type 4ALPS type IVALPS4NRAS autoimmune lymphoproliferative syndromeRALDRAS-associated autoimmune leukoproliferative diseaseRAS-associated autoimmune leukoproliferative disorderRAS-associated autoimmune lymphoproliferative syndrome type IV, somaticautoimmune lymphoproliferative syndrome caused by mutation in NRASautoimmune lymphoproliferative syndrome type 4autoimmune lymphoproliferative syndrome type IVautoimmune lymphoproliferative syndrome, type 4

Definition

RAS-associated autoimmune leukoproliferative disease (RALD) is a rare genetic disorder characterized by monocytosis, autoimmune cytopenias, lymphoproliferation, hepatosplenomegaly, and hypergammaglobulinemia.