/Duane retraction syndrome 3 with or without deafness

Duane retraction syndrome 3 with or without deafness

Rare Disease

MONDO:0014880

Also Known As

DURS3Duane retraction syndrome 3 with or without deafnessDuane retraction syndrome caused by mutation in MAFBMAFB Duane retraction syndromeDuane retraction syndrome 3Duane syndrome type 3

Definition

Duane syndrome type 3 is a disorder of eye movement.The affected eye, or eyes, has limited ability to move both inward toward the nose and outward toward the ears. The eye opening narrows and the eyeball pulls in when looking inward toward the nose. About 15 percent of all cases of Duane syndrome are type 3. Most cases occur without other signs and symptoms.In most people with Duane syndrome type 3, the cause is unknown; but it can sometimes be caused by mutations in the CHN1 gene and inherited in an autosomal dominant fashion.