/progressive non-fluent aphasia

progressive non-fluent aphasia

Rare Disease

MONDO:0015059

Also Known As

Agramatic variant of PPAAgramatic variant of primary progressive aphasiaPrimary Progressive Nonfluent aphasianon-fluent variant PPAnon-fluent primary progressive aphasia

Definition

Progressive non-fluent aphasia (PNFA) is a form of frontotemporal dementia (FTD), characterized by agrammatism, laborious speech, alexia, and agraphia, frequently accompanied by apraxia of speech (AOS). Language comprehension is relatively preserved.