/Bartter syndrome

Bartter syndrome

Rare Disease

MONDO:0015231

Also Known As

Bartter diseaseBartter's syndromealdosteronism with hyperplasia of the adrenal cortexhypokalemic alkalosisrenal tubular normotensive hypokalemic alkalosis with hypercalciuriasalt-losing tubular disorder, Henle's loop typesalt-wasting tubulopathy, Henle's loop typePotassium wastinghypokalemic alkalosis with hypercalciuria

Definition

Bartter syndrome is a group of rare renal tubular disease characterized by impaired salt reabsorption in the thick ascending limb of Henle's loop and clinically by the association of hypokalemic alkalosis, hypercalciuria/nephrocalcinosis, increased levels of plasma renin and aldosterone, low blood pressure and vascular resistance to angiotensin II.