/Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease

Rare Disease

MONDO:0015626

Also Known As

hereditary motor and sensory neuropathyhereditary sensorimotor neuropathyCMTCMT - Charcot-Marie-Tooth diseaseCMT/HMSNCharcot Marie Tooth muscular atrophyCharcot-Marie-Tooth diseaseCharcot-Marie-Tooth hereditary neuropathyperoneal muscular atrophyCharcot Marie Tooth diseaseCharcot-Marie-Tooth disease/hereditary motor and sensory neuropathy

Definition

An inherited degenerative disorder involving the peripheral nerves. It is caused by mutations in the genes that are responsible for the production of proteins necessary for the function and structure of the peripheral nerves. It is characterized by muscle atrophy and weakness in the feet, legs, hands, and arms and loss of sensation in the limbs.