/primary ciliary dyskinesia

primary ciliary dyskinesia

Rare Disease

MONDO:0016575

Also Known As

Kartagener syndromeKartagener's syndromePCDciliary motility disorderimmotile ciliary syndromeDextrocardia bronchiectasis and sinusitisDextrocardia-bronchiectasis-sinusitis syndromeICSImmotile cilia syndrome, Kartagener typePrimary ciliary dyskinesia and situs inversusPrimary ciliary dyskinesia, Kartagener typeSiewert syndromebronchiectasis, chronic sinusitis and dextrocardia syndromeciliary dyskinesia primary

Definition

A rare, genetically heterogeneous, primarily respiratory disorder characterized by chronic upper and lower respiratory tract disease. Approximately half of PCD patients have an organ laterality defect (situs inversus totalis or situs ambiguus/heterotaxy).