/hairy cell leukemia variant

hairy cell leukemia variant

Rare Disease

MONDO:0017600

Also Known As

HCL-VHCL-vhairy cell leukemia variantleukemic reticuloendotheliosis variantprolymphocytic variant of HCLprolymphocytic variant of hairy cell leukaemiaprolymphocytic variant of hairy cell leukemia

Definition

Hairy Cell Leukemia variant (HCL-V) is defined as a rare and indolent form of small, mature, B-cell leukemia characterized by splenomegaly, an elevated white blood cell (WBC) count and hyper-cellular bone marrow. HCL-V is more aggressive and resistant to therapy than classical HCL (HCL-C).