/primary lymphoma of the conjunctiva

primary lymphoma of the conjunctiva

Rare Disease

MONDO:0017907

Also Known As

conjunctiva lymphomaconjunctiva primary organ-specific lymphomalymphoma of conjunctivaprimary lymphoid conjunctival tumorprimary lymphoid conjunctival tumourprimary organ-specific lymphoma of conjunctiva

Definition

Primary lymphoma of the conjunctiva is an extremely rare clonal lymphoid proliferation of the ocular surface, with an indolent course. Clinically it presents with treatment-resistant conjunctivitis, ptosis, excessive tear production or as a painless, salmon-pink, ''fleshy'' patch, with a smooth or multinodular surface, on the bulbar conjunctiva. Histologically it is usually B-cell Non-Hodgkin lymphoma (most often extranodal marginal zone B-cell lymphoma, followed by follicular and diffuse large B-cell lymphoma), with conjunctival T-cell Non-Hodgkin lymphoma being very rare.