ABeta amyloidosis, Iowa type

Rare Disease

MONDO:0017946

Also Known As

ABetaD23N amyloidosisHCHWA, Iowa typecerebral amyloid angiopathy, APP-related, Iowa varianthereditary cerebral haemorrhage with amyloidosis, Iowa typehereditary cerebral hemorrhage with amyloidosis, Iowa type

Definition

Hereditary cerebral hemorrhage with amyloidosis (HCHWA), Iowa type is a form of HCHWA characterized by age of onset between 50-66 years of age, memory impairment, myoclonic jerks, expressive dysphagia, short-stepped gait, personality changes and lobar intracerebral hemorrhages.