Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production.
Comprehensive, easy-to-understand information about this condition
Checking for content...
prenatal-onset spinal muscular atrophy with congenital bone fractures
MONDO:0000209
spinal muscular atrophy
MONDO:0001516
familial amyotrophic lateral sclerosis
MONDO:0005144
neurogenic scapuloperoneal syndrome, Kaeser type
MONDO:0008407
riboflavin transporter deficiency
MONDO:0008891
motor neuron disease with dementia and ophthalmoplegia
MONDO:0010869