A group of very rare glomerular diseases, composed of immunotactoid glomerulopathy (ITG) and non-amyloid fibrillary glomerulopathy (non-amyloid FGP), that are characterized by mesangial deposition of monoclonal microtubular or polyclonal fibrillar deposits. Both present clinically with nephrotic range proteinuria, hematuria and renal insufficiency leading to renal failure in many cases. ITG is more likely to manifest with underlying lymphoproliferative disease, hypocomplementemia, dysproteinemia, monoclonal gammopathy or occult cryoglobulinemia. Non-amyloid FGP is 10 times more frequent than ITG.
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glomerulosclerosis
MONDO:0000490
glomerulonephritis
MONDO:0002462
fibronectin glomerulopathy
MONDO:0007671
congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization
MONDO:0019068
collagen type III glomerulopathy
MONDO:0019396
non-amyloid fibrillary glomerulopathy
MONDO:0019990