/pancreatic neuroendocrine tumor

pancreatic neuroendocrine tumor

Rare Disease

MONDO:0019954

Also Known As

islet cell tumorislet cell tumors - pancreasislet cell tumors of the pancreasislet cell tumourislet cell tumours - pancreasislet cell tumours of the pancreaspancreatic NETpancreatic neuroendocrine tumorwell differentiated pancreatic endocrine neoplasmwell differentiated pancreatic endocrine tumorwell differentiated pancreatic endocrine tumourwell-differentiated NEN of pancreaswell-differentiated neuroendocrine neoplasm of pancreaswell-differentiated pancreatic NENwell-differentiated pancreatic neuroendocrine neoplasmPANETneuroendocrine tumor of pancreasneuroendocrine tumour of pancreaspancreatic endocrine tumorpancreatic endocrine tumour

Definition

Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma).