/thymic neuroendocrine tumor

thymic neuroendocrine tumor

Rare Disease

MONDO:0019964

Also Known As

neuroendocrine neoplasm of thymusthymus NETthymus neuroendocrine neoplasmthymus neuroendocrine tumorthymus neuroendocrine tumor, well differentiated, low or intermediate gradethymus neuroendocrine tumour

Definition

Thymic endocrine tumor is a rare, malignant, primary thymic neoplasm originating from neuroendocrine cells, presenting as a mass within the anterior mediastinum. Patients typically present with nonspecific symptoms, such as chest pain, cough, shortness of breath, or in some cases, superior vena cava syndrome, although patients could be asymptomatic during the early stages or present with multiple endocrine neoplasia type I. Ectopic production of ACTH and serotonin can lead to Cushing syndrome and carcinoid sydrome, respectively.