/familial partial lipodystrophy

familial partial lipodystrophy

Rare Disease

MONDO:0020088

Also Known As

FPLDKoberling-Dunnigan syndromecongenital partial lipodystrophygenetic partial lipodystrophylipodystrophy, familial partial

Definition

Familial partial lipodystrophy (FPLD) is a group of rare genetic lipodystrophic syndromes characterized, in most cases, by fat loss from the limbs and buttocks, from childhood or early adulthood, and often associated with acanthosis nigricans, insulin resistance, diabetes, hypertriglyceridemia and liver steatosis.