/primary mediastinal large B-cell lymphoma

primary mediastinal large B-cell lymphoma

Rare Disease

MONDO:0020323

Also Known As

B-cell diffuse large cell lymphoma of mediastinumB-cell diffuse large cell lymphoma of the mediastinumMed-DLBCLPMBLPMLCLlarge cell lymphoma of the mediastinummediastinal (thymic) large B-cell lymphomamediastinal B-cell diffuse large cell lymphomamediastinal diffuse large cell lymphoma with sclerosismediastinal diffuse large-cell lymphoma with sclerosismediastinal large B-cell lymphomaprimary mediastinal clear cell lymphoma of B-cell typeprimary mediastinal large B-cell lymphomaprimary mediastinal (thymic) large B-cell lymphomaprimary mediastinal B-cell lymphoma

Definition

A large B-cell non-Hodgkin lymphoma arising in the mediastinum. Morphologically it is characterized by a massive diffuse lymphocytic proliferation associated with compartmentalizing fibrosis. Response to intensive chemotherapy, with or without radiotherapy, is usually good. (WHO, 2001)