/late-onset familial hypoaldosteronism

late-onset familial hypoaldosteronism

Rare Disease

MONDO:0035321

Also Known As

Late-onset familial hyperreninemic hypoaldosteronismMild aldosterone synthase deficiency

Definition

A rare form of familial hypoaldosteronism characterized by adult onset of subnormal plasma aldosterone with elevated plasma renin activity, hyperkalemia, metabolic acidosis, and hypotension. Signs and symptoms are typically mild, and affected individuals may be clinically asymptomatic and diagnosed only after biochemical screening.