Any recessive immunodeficiency (ID), with or without ectodermal dysplasia (EDA), in which the cause of the disease is mutation in the IKBKG gene. ID/EDA-ID patients, always males, are hemizygous for an IKBKG (NEMO) mutation that preserves residual NF-κB activation (hypomorphic mutations) and may also present with osteopetrosis and lymphoedema (OL-EDA-ID).
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B cell deficiency
MONDO:0002211
T-cell immunodeficiency
MONDO:0003780
complement deficiency
MONDO:0003832
myalgic encephalomeyelitis/chronic fatigue syndrome
MONDO:0005404
hypoproteinemia, hypercatabolic
MONDO:0009434
anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome
MONDO:0010295