A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding.
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relapsed/refractory diffuse large B-cell lymphoma
MONDO:0000901
breast diffuse large B-cell lymphoma
MONDO:0006117
colorectal diffuse large B-cell lymphoma
MONDO:0006158
gastric diffuse large B-cell lymphoma
MONDO:0006223
liver diffuse large B-cell lymphoma
MONDO:0006268
primary cutaneous diffuse large B-cell lymphoma, Leg type
MONDO:0006383