/familial periodic paralysis

familial periodic paralysis

Rare Disease

MONDO:0000995

Also Known As

familial periodic paralysishereditary periodic paralysis (disease)familial periodic paralysesfamilial periodic paralyzesgenetic periodic paralysisnormokalemic periodic paralysesnormokalemic periodic paralysisnormokalemic periodic paralyzesparalysis, familial periodicparalysis, normokalemic periodicparalyzes, normokalemic periodicperiodic paralysis, familialperiodic paralysis, normokalemicperiodic paralyzes, familialperiodic paralyzes, normokalemic

Definition

A group of genetic neurological disorders caused by mutations in genes involved in the sodium and calcium channels in nerve cells. It is characterized by episodes of muscle paralysis in which the affected muscles become flaccid and the deep tendon reflexes disappear. Between the episodes the affected muscles usually work normally.