/Andersen-Tawil syndrome

Andersen-Tawil syndrome

Rare Disease

MONDO:0008222

Also Known As

ATSAndersen cardiodysrhythmic periodic paralysisAndersen syndromeAndersen-Tawil syndromeLQT7Potassium-sensitive cardiodysrhythmic typelong QT syndrome 7long QT syndrome type 7Potassium-sensitive periodic paralysis, ventricular ectopy, and dysmorphic featurescardiodysrhythmic potassium-sensitive periodic paralysisperiodic paralysis, Potassium-sensitive cardiodysrhythmic type

Definition

Andersen's syndrome (AS) is a rare disorder characterized by periodic muscle paralysis, prolongation of the QT interval with a variety of ventricular arrhythmias (leading to predisposition to sudden cardiac death) and characteristic physical features: short stature, scoliosis, low-set ears, hypertelorism, broad nasal root, micrognathia, clinodactyly, brachydactyly and syndactyly.