/severe pre-eclampsia

severe pre-eclampsia

Rare Disease

MONDO:0001641

Also Known As

Preeclampsia with severe featuresantepartum severe pre-eclampsiapostpartum severe pre-eclampsiasevere pre-eclampsia, with deliverysevere preeclampsia

Definition

Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.