/maturity-onset diabetes of the young type 2

maturity-onset diabetes of the young type 2

Rare Disease

MONDO:0007453

Also Known As

GCK maturity-onset diabetes of the young (disease)GCK-associated diabetes mellitusMODY 2 monogenic diabetes type 2MODY glucokinase-relatedMODY type 2MODY, type IIMODY2glucokinase-associated diabetes mellitusmaturity onset diabetes of the Young, type 2maturity-onset diabetes of the young (disease) caused by mutation in GCKMODY, glucokinase-relatedMODY, type 2diabetes mellitus MODY type 2maturity-onset diabetes of the young, type 2type 2 maturity-onset diabetes of the young

Definition

Monogenic diabetes caused by inactivating mutation(s) in the GCK gene, encoding glucokinase. Heterozygous GCK mutations may manifest as mild hyperglycemia, which is not progressive, and usually requires no treatment. Homozygous GCK mutations result in permanent neonatal diabetes.