/hereditary spastic paraplegia 19

hereditary spastic paraplegia 19

Rare Disease

MONDO:0011785

Also Known As

SPG19autosomal dominant spastic paraplegia 19autosomal dominant spastic paraplegia type 19hereditary spastic paraplegia type 19spastic paraplegia 19spastic paraplegia 19, autosomal dominant

Definition

Autosomal dominant spastic paraplegia type 19 is a pure form of hereditary spastic paraplegia characterized by a slowly progressive and relatively benign spastic paraplegia presenting in adulthood with spastic gait, lower limb hyperreflexia, extensor plantar responses, bladder dysfunction (urinary urgency and/or incontinence), and mild sensory and motor peripheral neuropathy.