/hereditary spastic paraplegia 37

hereditary spastic paraplegia 37

Rare Disease

MONDO:0012766

Also Known As

SPG37autosomal dominant spastic paraplegia 37autosomal dominant spastic paraplegia type 37hereditary spastic paraplegia type 37spastic paraplegia 37, autosomal dominant

Definition

Autosomal dominant spastic paraplegia type 37 is a pure form of hereditary spastic paraplegia characterized by a childhood- to adulthood-onset of slowly progressive spastic gait, extensor plantar responses, brisk tendon reflexes in arms and legs, decreased vibration sense at ankles and urinary dysfunction. Ankle clonus is also reported in some patients.