/yolk sac tumor of central nervous system

yolk sac tumor of central nervous system

Rare Disease

MONDO:0016739

Also Known As

CNS yolk Sac tumorCNS yolk Sac tumourcentral nervous system yolk Sac tumorcentral nervous system yolk Sac tumourendodermal sinus tumor of CNSendodermal sinus tumor of central nervous systemendodermal sinus tumour of CNSendodermal sinus tumour of central nervous systemintracranial endodermal sinus tumorintracranial endodermal sinus tumourintracranial yolk sac tumorintracranial yolk sac tumouryolk Sac tumor of CNSyolk Sac tumor of central nervous systemyolk Sac tumor of the CNSyolk Sac tumor of the central nervous systemyolk Sac tumour of CNSyolk Sac tumour of central nervous systemyolk Sac tumour of the CNSyolk Sac tumour of the central nervous systemyolk sac tumor of CNSyolk sac tumour of CNS

Definition

A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells - putatively representing yolk sac endoderm - set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)