/Ewing sarcoma of bone

Ewing sarcoma of bone

Rare Disease

MONDO:0002625

Also Known As

Ewing sarcoma of boneEwing's sarcoma of boneEwing's sarcoma, osseousEwing's sarcoma/bone peripheral primitive neuroectodermal tumorEwing's sarcoma/bone peripheral primitive neuroectodermal tumourbone Ewing sarcomabone Ewing's sarcomabone localised Ewing sarcomabone localised Ewing's sarcomabone localized Ewing sarcomabone localized Ewing's sarcomabone tissue Ewing sarcomalocalised skeletal Ewing's sarcomalocalized skeletal Ewing's sarcomaosseous Ewing's sarcomaosseous Ewing's tumorosseous Ewing's tumourskeletal Ewing's sarcomaskeletal Ewing's tumorskeletal Ewing's tumour

Definition

A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.