/acute myeloid leukemia with 11q23 abnormalities

acute myeloid leukemia with 11q23 abnormalities

Rare Disease

MONDO:0020317

Also Known As

AML with 11q23 abnormalitiesAML with t(9;11)(p22;q23); MLLT3-MLLacute myeloid Leukaemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2Aacute myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2Aacute myeloid leukaemia with 11q23 (MLL) abnormalitiesacute myeloid leukaemia with MLL abnormalitiesacute myeloid leukaemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2Aacute myeloid leukaemia with t(9;11)(p22;q23); MLLT3-MLLacute myeloid leukemia with 11q23 (MLL) abnormalitiesacute myeloid leukemia with MLL abnormalitiesacute myeloid leukemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2Aacute myeloid leukemia with t(9;11)(p22;q23); MLLT3-MLL

Definition

An acute myeloid leukemia associated with t(9;11)(p22.3;q23.3) and MLLT3-KMT2A fusion protein expression. Morphologically it usually has monocytic features. It may present at any age but it is more commonly seen in children. Patients may present with disseminated intravascular coagulation.