/acute myeloid leukemia, KIT gene mutation

acute myeloid leukemia, KIT gene mutation

Rare Disease

MONDO:0100420

Also Known As

AML, C-KIT MutationAML, CD117 Gene MutationAML, CD117 MutationAML, KIT Proto-Oncogene Tyrosine Protein Kinase Gene MutationAML, KIT gene mutationAML, V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog Gene MutationAML, c-KIT Gene Mutation

Definition

Any acute myeloid leukemia that has the chromosomal anomaly KIT gene mutation. (A molecular genetic abnormality that refers to mutation of the c-kit (CD117) proto-oncogene. It is associated with the development of gastrointestinal stromal tumor and gastrointestinal autonomic nerve tumor. It has also been described in acute myeloid leukemias, dysgerminomas, and seminomas.)